Translational Center on Biomaterials for Orthopedic and Dental applications

Prototype Development of in vivo tested HDPE based biocompatible composite with HA/Al2O3 Ceramic Fillers as Acetabular Cup for Total Hip Replacement

Principal Investigator

Bikramjit Basu
Materials Research Centre,
Indian Institute of Science, Bangalore
Email: bikram@mrc.iisc.ernet.in
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Co-Principal Investigator

Suryasarathi Bose
Department of Materials Engineering,
Indian Institute of Science, Bangalore
Email:
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Co-Investigators

R. Joseph Ben Singh
Central Institute for Plastic Engineering and Technology, Chennai
Email:
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K. Rajashekaran
Central Institute for Plastic Engineering and Technology, Chennai
Email:
Website
Biswanath Kundu
Bioceramics & Coating Division,
CSIR-Central Glass & Ceramic Research Institute, Kolkata
Email:
Website
Varmsi Krishna Balla
Bioceramics & Coating Division,
CSIR-Central Glass & Ceramic Research Institute, Kolkata
Email:
Website
D. C. Sundaresh
M S Ramaiah University of Applied Sciences, Bangalore
Email:
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Amit Roy Chowdhury
Indian Institute of Engineering Science & Technology(IIEST), Shibpur
Email:
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Kantesh Balani
Indian Institute of Technology Kanpur
Email:
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A. Sabareeswaran
Biomedical Technology Wing,
Sree Chitra Tirunal Institute for Medical Sciences and Technology (SCTIMST), Trivandrum
Email:
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Objectives of the Project

To tailor the chemical synthesis route to establish the surface modification of carbon nanotubes and enhancement of the interfacial adhesion with HDPE

To optimise the chemical sysnthesis conditions to chemically couple ceramic fillers (HA, Al2O3) with polymeric matrix (HDPE)

To develop lab scale component of HDPE-CNT and HDPE-HA-Al2O3 hybrid composites and determination of their mechanical properties

Development of prototype for polymer acetabular socket for hip implant with dimensions specially suited for Indian patients after consultation with orthopaedic surgeons.

To establish the non-cytotoxic properties of the wear debris particles

To carry out hip simulator experiments using HIP simulator at CGCRI to assess the performance under cyclic fatigue and tribological conditions under in vivo simulated physiological scenario